6.1 CNS Pharm Flashcards
(41 cards)
1
Q
ACh function
A
cognitive function
memory
movement
2
Q
DA function
A
posture voluntary movements prolactin secretion (inhibited) affect emotion cognition
3
Q
NE function
A
responses to external stimuli arousal/attention learning memory mood
4
Q
5-HT function
A
mood fear/anxiety emotional memory inhibit sexual responses nausea/vomiting
5
Q
histamine function
A
arousal
body temp
vascular
6
Q
GABA function
A
major inhibitory NT in CNS
7
Q
glycine function
A
pain
respiration
motor coordination
8
Q
glutamate function
A
major fast excitatory NT in CNS
9
Q
opioid peptide function
A
miosis nausea constipation cough suppression histamine release facial itching
10
Q
endocannabinoid function
A
mood appetite pain sensation smooth muscle tone immune function
11
Q
M1
A
ACh
excitatory
metabotropic
postsynaptic
12
Q
M2
A
ACh
inhibitory
metabotropic
postsynaptic
13
Q
Nn
A
ACh
excitatory
ionotropic
postsynaptic
14
Q
D1
A
DA excitatory metabotropic postsynaptic heteroreceptors
15
Q
D2
A
DA inhibitory metabotropic postsynaptic somatodendritic autoreceptors axon terminal autoreceptors
16
Q
alpha 1
A
NE
excitatory
metabotropic
postsynaptic
17
Q
alpha 2
A
NE inhibitory metabotropic postsynaptic presynaptic autoreceptors (decr Ca2+ influx)
18
Q
beta
A
NE
excitatory
metabotropic
postsynaptic
19
Q
5HT1A
A
5HT inhibitory metabotropic postsynaptic somatodendritic
20
Q
5HT1D
A
5HT inhibitory metabotropic postsynaptic axon terminal
21
Q
5HT2A
A
5HT
excitatory
metabotropic
postsynaptic
22
Q
5HT3
A
5HT
excitatory
ionotropic
postsynaptic
23
Q
H1
A
histamine
excitatory
neurons, blood vessels, glia
24
Q
GABAA
A
GABA
inhibitory
ionotropic
postsynaptic
25
glycine receptor
glycine
inhibitory
ionotropic
26
glutamate receptors
excitatory ionotropic
| inhibitory metabotropic
27
Mu
opioid
inhibitory
metabotropic
28
Kappa
opioid
inhibitory
metabotropic
29
CB1
endocannabinoids
inhibitory
metabotropic
30
receptor in CTZ
5HT3
31
MAO-A substrates
DA
NE
5HT
tyramine
32
MAO-B substrates
DA
| tyramine
33
COMT substrates
DA
NE
E
levodopa
34
opioid receptor for sedation
mu
35
opioid receptor for euphoria
mu
36
opioid receptor with significant respiratory depression
mu
37
opioid receptor for analgesia
mu and kappa
38
opioid receptor for hypnosis
kappa
39
opioid receptor for dysphoria
kappa
40
opioid receptor with less respiratory depression
kappa
41
strychnine
an anticonvulsant that is a glycine antagonist
