4.12 pharm beta antag

Question 0

Nadolol mech

Answer 0

Inverse agonist

Question 1

Propranolol mech

Answer 1

Neutral antag

Question 2

Pindolol mech

Answer 2

Antag with slight positive agonist

Question 3

Timolol mech

Answer 3

Antagonist

Question 4

Metoprolol mech

Answer 4

β1 inverse agonist

Question 5

Acebutolol mech

Answer 5

β1 antag

Question 6

Esmolol mech

Answer 6

Fast acting β1 antag

Question 7

Butoxamine mech

Answer 7

β2 antag

Question 8

Labetalol mech

Answer 8

3:1 β:α antag

Question 9

Carvedilol mech

Answer 9

10:1 β:α antag

Question 10

Powerful antioxidant

Answer 10

Carvedilol

Question 11

Used for CHF

Answer 11

Metoprolol

Carvedilol

Question 12

Helps treat arrhythmias

Answer 12

Propranolol

Maybe Carvedilol

Question 13

For MI

Answer 13

Nadolol
Pindolol
Propranolol
Carvedilol
Atenolol
Metoprolol

Question 14

Preferred for asthmatics

Answer 14

Metoprolol
Acebutolol
Esmolol

Question 15

β1 selective antagonists or inverse agonists

Answer 15

Metoprolol
Acebutalol
Esmolol

Question 16

Common chemical structure of beta blockers

Answer 16

Bulk on amine (favors β)

3 carbon chain on amine (favors antagonism)

Question 17

ADRs for all β blockers

Answer 17

Rebound ischemia
Fatigue
Vivid dreams
Insomnia
Hallucinations
Exercise intolerance

Question 18

Contraindications for all β blockers & for non selective

Answer 18

Late stage CHF
Asthma (for non selective)
AV node conductance disturbances
Hypoglycemia

Question 19

Used in urgent hospital settings where β blockade is needed

Answer 19

Esmolol

Question 20

Has a short duration because rapidly metabolized by esterases

Answer 20

Esmolol

Question 21

Impotence drug acting equally on PDE5&PDE6

Answer 21

Sildenafil

Question 22

Impotence drug selective for PDE5

Answer 22

Tadalafil

Question 23

Disturbs color perception

Answer 23

Sildenafil

Question 24

Fast onset impotence drugs

Answer 24

Vardenafil | Avanafil