Pharm 5 Flashcards
(20 cards)
Another pharmacological effect of a drug is what type of ADR
Type A
An extension of a primary effect is what type of ADR
Type A
An unusual or unexpected reaction is what type of ADR
Type B
A immune mediated reaction is what type of ADR
Type B
Opioid causing constipation is what type of ADR
Type A
Lisinopril causing angioedema is what type of ADR
Type B
What two drugs mixed together in IV makes a salt
Heparin (acid) and antihistamine (base)
What is chelated (and not absorbed in stomach) if taken with antacid like maalox
Tetracycline
What two drugs bind to same protein and must be titrated if used together
Tolbutamide
Oral anticoagulants
How do you alkalinize the urine
NaHCO3 (which promotes excretion of aspirin)
Grapefruit juice shouldn’t be used with
Statins like atorvastatin
What drugs induce activity of enzymes
Barbiturates like thiopental
Drugs that interact at site of action
Anticholinergic and xerostomic (merpiridine and promethazine)
Opioid analgesics and other CNS depressant (diazepam, ethanol)
Most dangerous period for baby in terms of drugs
Embryonic period (18-55 days)
Pregnancy category A
Vitamins
Thyroid hormones
Pregnancy category B
Acetaminophen
Penicilin
Oxycodone
Pregnancy category C
Sertraline (SSRI)
Pseudoephedrine (decongestant)
Pregnancy category D
Lithium (bipolar)
Phenytoin (and most benzos)
Pregnancy category X
Statins
Isotretinoin
Thalidomide
NSAIDS and pregnancy category switching
Category B in trimester 1 and 2
Category D in 3rd trimester (premature closure of ductus arteriosus)