Pharm 5 Flashcards

(20 cards)

0
Q

Another pharmacological effect of a drug is what type of ADR

A

Type A

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1
Q

An extension of a primary effect is what type of ADR

A

Type A

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2
Q

An unusual or unexpected reaction is what type of ADR

A

Type B

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3
Q

A immune mediated reaction is what type of ADR

A

Type B

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4
Q

Opioid causing constipation is what type of ADR

A

Type A

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5
Q

Lisinopril causing angioedema is what type of ADR

A

Type B

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6
Q

What two drugs mixed together in IV makes a salt

A

Heparin (acid) and antihistamine (base)

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7
Q

What is chelated (and not absorbed in stomach) if taken with antacid like maalox

A

Tetracycline

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8
Q

What two drugs bind to same protein and must be titrated if used together

A

Tolbutamide

Oral anticoagulants

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9
Q

How do you alkalinize the urine

A

NaHCO3 (which promotes excretion of aspirin)

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10
Q

Grapefruit juice shouldn’t be used with

A

Statins like atorvastatin

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11
Q

What drugs induce activity of enzymes

A

Barbiturates like thiopental

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12
Q

Drugs that interact at site of action

A

Anticholinergic and xerostomic (merpiridine and promethazine)

Opioid analgesics and other CNS depressant (diazepam, ethanol)

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13
Q

Most dangerous period for baby in terms of drugs

A

Embryonic period (18-55 days)

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14
Q

Pregnancy category A

A

Vitamins

Thyroid hormones

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15
Q

Pregnancy category B

A

Acetaminophen
Penicilin
Oxycodone

16
Q

Pregnancy category C

A

Sertraline (SSRI)

Pseudoephedrine (decongestant)

17
Q

Pregnancy category D

A

Lithium (bipolar)

Phenytoin (and most benzos)

18
Q

Pregnancy category X

A

Statins
Isotretinoin
Thalidomide

19
Q

NSAIDS and pregnancy category switching

A

Category B in trimester 1 and 2

Category D in 3rd trimester (premature closure of ductus arteriosus)