Connective Tissue Flashcards
(16 cards)
Type 4 collagen is made by
Epithelial cells
What stain would you use to see reticular fibers?
Silver stain
Disease that involves defect in collagen synthesis
Ehlers-Danlos syndrome
Fibrillin attaches to and inactivated
TGFβ
Amyloidosis is characterized by
Large beta sheets that can’t be broken down
Alzheimer’s is characterized by
Amyloid deposits around neurons
What do metalloproteinases do?
Break down extracellular matrix / basement membrane
Plasma cells are derived from
B lymphocytes
Difference between mesenchymal cells and mucoid cells
Mesenchymal - fetal face, basophilic
Mucoid - umbilical cord, eosinophilic / acidophilic, see collagen
How to tell between uni and multilocular fat
Multilocular looks foamier
Fibrous scars are made of
Collagen I
Elastin is a hydrophobic protein deposited between
Fibrillin microfibrils
Metalloproteinases are produced by
Connective tissue
What ECM protein is found in embryonic tissues
Tenascin
What ECM protein binds to collagen, heparin, and CAMs for adhesion
Fibronectin
4 main outcomes of acute inflammation
Resolution
Healing by fibrosis
Abscess formation
Chronic inflammation
