4.22 path derm 1 Flashcards

(36 cards)

0
Q

Bump small and big

A

Papule

Plaque

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1
Q

Flat, small and big

A

Macule

Patch

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2
Q

Blister small and big

A

Vesicle

Bulla

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3
Q

Blister with pus

A

Pustule

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4
Q

Urticaria is a

A

Wheal

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5
Q

Bump medium (>1cm) and big (>2 cm)

A

Nodule

Tumor

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6
Q

Pruritic with erythematous borders

A

Wheals (urticaria)

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7
Q

Flaking of keratin

A

Scale

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8
Q

From chronic rubbing

A

Lichenification

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9
Q

Thick stratum corneum

A

Hyperkeratosis

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10
Q

Keratinization with retained nuclei

A

Parakeratosis

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11
Q

Thickening of epidermis

A

Acanthosis

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12
Q

Thick stratum granulosum

A

Hypergranulosis

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13
Q

Hyperplasia of dermal papilla

A

Papillomatosis

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14
Q

Clinical manifestation of papillomatosis

A

Verruca (wart)

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15
Q

Munro abscesses (neutrophil cluster in parakeratosis)

16
Q

Loss of epidermis

Have granulation tissue (neutrophils + blood vessels)

17
Q

Spongiosis is characteristic of what clinical disease

18
Q

Intercellular edema in epidermis

Separated squamous cells, but still held together by desmosomes

19
Q

Intracellular edema

A

Hydronic swelling / ballooning

20
Q

Loss of intercellular cohesion between keratinocytes

21
Q

Abnormal premature keratinization within cells below stratum granulosum

22
Q

Formations of vacuoles within or adjacent to cells, usually in basal cell membrane zone

A

Vacuolization

23
Q

Common in drug reactions

A

Vacuolization

24
Distinguish lichen planus from lichen simplex chronicus
Have vacuolization
25
Lymphocytes migrating into epidermis
Exocytosis
26
Linear pattern of melanocyte proliferation within the epidermal basal cell layer
Lentiginous
27
Rough erythematous or brown plaques with small scale
Actinic keratosis
28
Precursor lesion to squamous cell carcinoma
Actinic keratosis
29
Topicals to treat actinic keratosis
Imiquimod | 5-FU
30
Erythematous scaly plaques (does not invade through basement membrane) with parakeratosis
Squamous cell carcinoma in situ
31
1st and 2nd common tumor arising on sun exposed skin
Basal cell carcinoma | Squamous cell carcinoma
32
Scaly plaques in early stage | Nodular and ulcerate in late stage
Squamous cell carcinoma
33
Causes of squamous cell carcinoma
Uv light Immuno suppression Industrial carcinogens
34
Pearly papilla with telangiectasias
Basal cell carcinoma
35
Disease that is associated with DNA mismatch repair / NPPCC
Muir-Torre syndrome